JOURNAL ARTICLE

Is fertility-sparing exogenous testosterone therapy a real thing?

  • Published In: Journal of Sexual Medicine, 2024, v. 21, n. 7. P. 582 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Asanad, Kian; Brannigan, Robert E 3 of 3

Abstract

The article discusses the potential for fertility-sparing exogenous testosterone therapy in men experiencing testosterone deficiency while seeking to maintain their fertility. It highlights the risks associated with traditional exogenous testosterone therapy, which can disrupt normal sperm production, and notes that some urologists may still prescribe it to men actively trying to conceive. The authors explore alternative approaches, such as combining low-dose human chorionic gonadotropin (hCG) with testosterone therapy, and using topical testosterone gel with aromatase inhibitors, particularly in adolescents with Klinefelter syndrome. They emphasize the need for further research to clarify the efficacy of these emerging therapies in preserving fertility outcomes. [Extracted from the article]

Additional Information

  • Source:Journal of Sexual Medicine. 2024/07, Vol. 21, Issue 7, p582
  • Document Type:Editorial
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:1743-6095
  • DOI:10.1093/jsxmed/qdae046
  • Accession Number:178778915
  • Copyright Statement:Copyright of Journal of Sexual Medicine is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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