JOURNAL ARTICLE

Antiepileptic Drugs as Prophylaxis for Seizures after Excision of Brain Tumors.

  • Published In: QJM: An International Journal of Medicine, 2024, v. 117. P. i154 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Ashour, Ahmed Maamoun; Fayed, Zeiad Yossry; Sabry Ismail, Ismail Hassan; Sherif Agiez, Mostafa Ahmed 3 of 3

Abstract

This article examines the efficacy of prophylactic antiepileptic drugs (AEDs) in preventing seizures after brain tumor excision in patients without a prior history of seizures. A review of studies from 2000 to 2021 found no statistically significant difference in postoperative seizure rates between patients who received AEDs and those who did not. The most commonly used AEDs were Phenytoin and Levetiracetam, and early seizures were the most frequent postoperative seizure type. The authors conclude that current evidence is insufficient to recommend routine prophylactic AED use for seizure prevention following brain tumor surgery.

Additional Information

  • Source:QJM: An International Journal of Medicine. 2024/06, Vol. 117, pi154
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:1460-2725
  • DOI:10.1093/qjmed/hcae070.356
  • Accession Number:178590527
  • Copyright Statement:Copyright of QJM: An International Journal of Medicine is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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