Development of a Nomogram and Risk Grouping System for Predicting 1-Year Overall Survival of Patients With Atypical Teratoid/Rhabdoid Tumors.

This article focuses on the development of a clinical nomogram and risk grouping system to predict 1-year overall survival in pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT), a rare and aggressive central nervous system malignancy. Using data from 54 patients treated at Xinhua Hospital affiliated with Shanghai Jiaotong University School of Medicine, the study identified age at diagnosis, extent of tumor resection, radiotherapy, and chemotherapy as independent prognostic factors incorporated into the nomogram. The model demonstrated good predictive accuracy (concordance index of 0.781) and was used to stratify patients into low-, intermediate-, and high-risk groups with significantly different survival outcomes. This tool aims to support personalized prognostic evaluation and guide treatment decisions, though further validation in larger, multicenter cohorts is needed.