Photobiomodulation-assisted surgical wound healing at palatal donor site area: a systematic review.

This systematic review critically examines the effects of photobiomodulation (PBM), also known as low-level laser therapy (LLLT), on healing of the palatal donor site following free gingival graft (FGG) surgery. Analyzing eight randomized clinical trials involving 284 healthy adult patients, the review found that PBM generally accelerated wound healing—evidenced by faster epithelialization, reduced wound area, and improved tissue color—particularly within the first two postoperative weeks. However, the impact of PBM on postoperative pain relief was inconsistent, with only two studies reporting significant reductions. Due to heterogeneity in laser parameters, treatment protocols, and outcome measures, a meta-analysis was not feasible, and the authors recommend future well-designed trials with standardized methodologies to establish definitive clinical guidelines.