JOURNAL ARTICLE

B - 114 Evaluation of the Montreal Cognitive Assessment Memory Index Score for Predicting Amnestic Mild Cognitive Impairment to Alzheimer's Clinical Syndrome Progression.

  • Published In: Archives of Clinical Neuropsychology, 2024, v. 39, n. 7. P. 1216 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Kronenberger, Oscar; Lacritz, Laura H; Nguyen, Trung P; Kaser, Alyssa; Longoria, Anthony; Lee, Diamond; Schaffert, Jeffrey 3 of 3

Abstract

This article evaluates the effectiveness of the Montreal Cognitive Assessment Memory Index Score (MoCA-MIS) and related MoCA measures in predicting progression from amnestic mild cognitive impairment (aMCI) to Alzheimer’s Clinical Syndrome (ACS). Using data from 353 mostly male, White, and well-educated individuals aged 50 and older with aMCI, the study found that baseline MoCA total score, delayed free recall score, and MIS cutoffs showed moderate sensitivity and specificity but were generally poor predictors of conversion to ACS over 3–6 years. An existing algorithm combining MoCA total score and MIS cutoffs demonstrated high specificity but very low sensitivity in this sample. These results indicate that MoCA-based cutoffs alone are insufficient for reliably forecasting cognitive decline in aMCI, underscoring the need for comprehensive longitudinal assessment.

Additional Information

  • Source:Archives of Clinical Neuropsychology. 2024/10, Vol. 39, Issue 7, p1216
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:0887-6177
  • DOI:10.1093/arclin/acae067.275
  • Accession Number:184163566
  • Copyright Statement:Copyright of Archives of Clinical Neuropsychology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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