JOURNAL ARTICLE

Cystectomy and lymphadenectomy – we now node how far to go!

  • Published In: BJU International, 2025, v. 135, n. 3. P. 425 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Santucci, Jordan; Perera, Sachin; Sathianathen, Niranjan; Perera, Marlon; Murphy, Declan; Lawrentschuk, Nathan 3 of 3

Abstract

The article discusses the results of two phase III randomized controlled trials, SWOG S1011 and German LEA AUO AB 25/02, which found that standard lymph node dissection (LND) during cystectomy for bladder cancer is sufficient, with no added benefit from extended LND. The trials showed no improvement in recurrence-free survival or overall survival with extended LND, and in fact, the SWOG trial reported a higher burden of adverse effects in the extended LND group. The studies caution against extending LND beyond the internal and external iliac lymph node chains, suggesting that a more limited LND is preferable. [Extracted from the article]

Additional Information

  • Source:BJU International. 2025/03, Vol. 135, Issue 3, p425
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:1464-4096
  • DOI:10.1111/bju.16599
  • Accession Number:184016345
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