JOURNAL ARTICLE

B - 09 Neuropsychological Impacts and Cognitive Effects of Pediatric Leukemia Treatment.

  • Published In: Archives of Clinical Neuropsychology, 2023, v. 38, n. 7. P. 1373 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Aronson, Rebecca; Stafford, Claire; Garcia-Lavin, Barbara 3 of 3

Abstract

This article focuses on the neuropsychological and cognitive late effects of pediatric Acute Lymphoblastic Leukemia (ALL) treatment. A review of 59 peer-reviewed studies found that ALL treatments, including chemotherapy and cranial radiotherapy (CRT), are associated with impairments in working memory, processing speed, attention, executive functioning, visuospatial and visuomotor skills, fine motor abilities, delayed memory, and declines in performance IQ and verbal abilities. The observed cognitive declines, particularly following CRT, may result from structural changes in brain white and gray matter. The study emphasizes the importance of healthcare providers addressing cognitive complaints in pediatric ALL patients to support treatment adherence, school reintegration, and psychological well-being, recommending further neuropsychological assessment when cognitive issues are reported.

Additional Information

  • Source:Archives of Clinical Neuropsychology. 2023/10, Vol. 38, Issue 7, p1373
  • Document Type:Abstract
  • Subject Area:Health and Medicine
  • Publication Date:2023
  • ISSN:0887-6177
  • DOI:10.1093/arclin/acad067.216
  • Accession Number:174274994
  • Copyright Statement:Copyright of Archives of Clinical Neuropsychology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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