JOURNAL ARTICLE

Effect of vasopressin infusion in refractory neonatal shock.

  • Published In: Journal of Neonatal - Perinatal Medicine, 2025, v. 18, n. 1. P. 86 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Thakur, Anup; Dangi, Sachin; Gehlawat, Rohit; Kler, Neelam; Garg, Pankaj; Fursule, Anurag 3 of 3

Abstract

The article focuses on evaluating the effect of vasopressin infusion in neonates with refractory shock, defined as shock unresponsive to standard inotropes and hydrocortisone. In a retrospective cohort study of 32 neonates treated in a level 3B neonatal intensive care unit in northern India, vasopressin administration was associated with significant improvements in systolic, diastolic, and mean blood pressure, as well as increased urine output after 48 hours. However, vasopressin therapy was also linked to a significant decrease in serum sodium levels. The study suggests vasopressin may serve as a rescue therapy in refractory neonatal shock but highlights the need for randomized controlled trials to confirm these findings.

Additional Information

  • Source:Journal of Neonatal - Perinatal Medicine. 2025/01, Vol. 18, Issue 1, p86
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:1934-5798
  • DOI:10.1177/19345798241296327
  • Accession Number:183569920
  • Copyright Statement:Copyright of Journal of Neonatal - Perinatal Medicine is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Looking to go deeper into this topic? Look for more articles on EBSCOhost.