JOURNAL ARTICLE

Bronchial Washing Using a Thin Versus a Thick Bronchoscope to Diagnose Pulmonary Tuberculosis: A Randomized Trial.

  • Published In: Clinical Infectious Diseases, 2023, v. 76, n. 2. P. 238 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Eom, Jung Seop; Park, Seyeon; Jang, Hyojin; Kim, Saerom; Yoo, Wan Ho; Kim, Soo Han; Mok, Jeongha 3 of 3

Abstract

This article evaluates the efficacy of using a thin bronchoscope for diagnosing pulmonary tuberculosis (PTB) in patients with negative sputum acid-fast bacilli (AFB) smear and tuberculosis (TB) polymerase chain reaction (PCR) tests or those unable to produce sputum. In a prospective randomized trial at a South Korean tertiary hospital, bronchial washing (BW) using a 4.0-mm thin bronchoscope under virtual bronchoscopic navigation (VBN) guidance showed a significantly higher TB detection rate by the Xpert MTB/RIF assay compared to conventional bronchoscopy with a 5.9-mm bronchoscope (72.4% vs. 43.5%). The investigational group also had a shorter median time to treatment initiation (2.0 vs. 4.0 days) and no increase in bronchoscopy-related complications. These findings suggest that thin bronchoscopy with VBN may improve rapid PTB diagnosis in challenging cases, though further multicenter studies are recommended to confirm generalizability.

Additional Information

  • Source:Clinical Infectious Diseases. 2023/01, Vol. 76, Issue 2, p238
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2023
  • ISSN:1058-4838
  • DOI:10.1093/cid/ciac789
  • Accession Number:161313994
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