JOURNAL ARTICLE

Structural elucidation and complete NMR spectral assignments of Monascus monacolin analogues.

  • Published In: Magnetic Resonance in Chemistry, 2024, v. 62, n. 8. P. 605 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Liu, Jiachen; Xu, Qingjiang; Wang, Xin; Shang, Xiaoya; Wang, Nan 3 of 3

Abstract

Three new monacolin analogues, 3,6‐dihydroxy‐monacolin P (1), 6‐methoxy monacolin S (2), and 6‐methoxy dehydromonacolin S (3), were isolated from a fraction that strongly inhibited 3‐hydroxy‐3‐methylglutaryl‐CoA reductase from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were determined through a combination of 1D and 2D NMR experiments, mass spectrometry analysis, and known literature reports. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Magnetic Resonance in Chemistry. 2024/08, Vol. 62, Issue 8, p605
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:0749-1581
  • DOI:10.1002/mrc.5447
  • Accession Number:178279801
  • Copyright Statement:Copyright of Magnetic Resonance in Chemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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