JOURNAL ARTICLE

Hemodynamic Variability During Drainage of Large Volumes of Malignant Ascites in Patients With Cancer.

  • Published In: Clinical Nursing Research, 2023, v. 32, n. 4. P. 815 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Kawamura, Tomoko; Tanaka, Noriyoshi; Hori, Megumi; Inoue, Ken-ichiro; Kawamura, Masahiko; Matsusaki, Keisuke 3 of 3

Abstract

This study investigated whether the variability in mean arterial pressure (MAP) during drainage of malignant ascites differs between large (5–10 L) and small (<5 L) volume removal in cancer patients undergoing cell-free and concentrated ascites reinfusion therapy (KM-CART). Results from 49 patients showed equivalence in MAP variability within ±20% between the two drainage volumes when performed under gravity flow at slow speed, indicating that removal of up to 10 L of ascites does not significantly affect MAP. Other hemodynamic and respiratory variables also showed no significant differences, supporting the safety of large-volume drainage using this method. These findings provide clinical guidance for safely managing malignant ascites drainage and may inform decision-making to improve patient outcomes and quality of life.

Additional Information

  • Source:Clinical Nursing Research. 2023/05, Vol. 32, Issue 4, p815
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2023
  • ISSN:1054-7738
  • DOI:10.1177/10547738231157157
  • Accession Number:163453263
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