Comments on "Severe bleeding in patients following "tubeless" percutaneous nephrolithotomy: Predictors of angioembolization".

The article critically examines a study on severe bleeding following "tubeless" percutaneous nephrolithotomy (PCNL) and factors linked to the need for angioembolization (AE). It highlights methodological concerns, including selection bias due to analyzing only patients with established severe bleeding, potential misclassification regarding nephrostomy tube placement, and inconsistencies in statistical reporting. The authors also note limitations in the statistical modeling approach, such as dichotomizing continuous variables and possible overfitting. While acknowledging the clinical importance of the findings for managing post-PCNL bleeding, the article emphasizes that the results should be interpreted as identifying factors associated with AE among patients already experiencing severe bleeding, rather than as predictors applicable to all PCNL cases. [Extracted from the article]