Genital verruciform xanthoma: A rare differential to genital warts.

This article focuses on verruciform xanthoma, a rare benign mucocutaneous growth typically found in the oral cavity but occasionally occurring on genital skin, where it can mimic sexually transmitted infections such as human papillomavirus (HPV)-related genital warts. The case of an 89-year-old man with a solitary scrotal lesion initially suspected to be a wart is presented; histopathological analysis after excision confirmed verruciform xanthoma, highlighting the importance of biopsy for accurate diagnosis. The lesion's etiology remains unclear with no established link to HPV, and excision is generally curative, although recurrence has been reported. This condition's rarity and clinical similarity to malignant or infectious lesions underscore the need for careful differential diagnosis to avoid unnecessary or ineffective treatments.