Cervical Cytological and Colposcopic abnormalities in Cases Using Combined Oral Contraceptive Pills.

Background: The fourth most frequent type of cancer and a major cause of death is cervical cancer. Because of its lengthy pre-invasive course, pap smears can be used as a routine screening tool to identify it. Aim: utilizing the Pap test to identify cervical dysplasia and colposcopy to confirm the diagnosis, as a way of prevention and early detection of premalignant cervical cancer lesions. Methods: 60 women using combined oral contraceptive pills undergo examination in outpatient clinics of the hospital of Zagazig University. This examination includes a PAP smear with colposcopic visualization if there are abnormal findings in the PAP smear to all involved patients. Results: 43.3% of cases were normal, 38.3% showed inflammatory changes, and 18.3% were abnormal. Among the abnormal results, 3.3% were classified as Low-Grade Squamous Intraepithelial Lesions (LG SIL), 11.7% were identified as Atypical Squamous Cells of Undetermined Significance (ASCUS), and 3.3% showed both ASCUS and atypical endocervical glands. There's no relation between the delivery method and PAP outcomes (p-value 0.49). Parity shows no significant association with abnormal PAP (P = 0.43). Prolonged use of OCP is significantly associated with abnormal PAP (P =0 .0022). Conclusions: Abnormal cytology is related substantially to longterm oral contraceptive pill use. [ABSTRACT FROM AUTHOR]