JOURNAL ARTICLE

Eruptive Palmoplantar Pigmentation Secondary to Anti‐Cancer Drugs: Clinical and Dermoscopic Evaluation.

  • Published In: International Journal of Dermatology, 2026, v. 65, n. 1. P. 145 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Bouraqqadi, Oumaima; Soughi, Meryem; Amaadour, Lamiae; Douhi, Zakia; Elloudi, Sara; Baybay, Hanane; Mellas, Nawfel; Mernissi, Fatima Zahra 3 of 3

Abstract

The article focuses on the clinical and dermoscopic characteristics of palmoplantar pigmentation (PPP) in patients undergoing chemotherapy, aiming to improve diagnostic accuracy and differentiate benign pigmentary changes from malignancy. A retrospective study of 300 chemotherapy patients revealed that 74 individuals developed PPP macules, primarily after starting treatment, with a mean age of 54 years. The study identified various chemotherapy agents associated with pigmentation, including capecitabine, doxorubicin, and taxanes, and highlighted the importance of dermoscopy in distinguishing chemotherapy-induced pigmentation from melanoma. The findings suggest that PPP is a common yet underreported side effect of chemotherapy that requires careful evaluation. [Extracted from the article]

Additional Information

  • Source:International Journal of Dermatology. 2026/01, Vol. 65, Issue 1, p145
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2026
  • ISSN:0011-9059
  • DOI:10.1111/ijd.17825
  • Accession Number:190327284
  • Copyright Statement:Copyright of International Journal of Dermatology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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