JOURNAL ARTICLE

Incidence and risk factors for low serum albumin concentrations in neonates evaluated for jaundice.

  • Published In: Journal of Neonatal - Perinatal Medicine, 2026, v. 19, n. 1. P. 97 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Rojsirikulchai, Napat; Keesukphan, Suchanun; Emrat, Kanuengnit; Kongurai, Prathana; Swatesutipun, Buranee; Rattanamalee, Rachaporn; Soonsawad, Sasivimon; Ruangkit, Chayatat 3 of 3

Abstract

This study focuses on the incidence and risk factors for low serum albumin concentrations (<3.0 g/dL) in neonates born at ≥35 weeks gestation who were evaluated for jaundice at three university hospitals in Thailand during 2023. Among 902 neonates assessed, 25.4% had hypoalbuminemia, which was significantly associated with lower gestational age, male sex, and clinical instability or sepsis. These findings suggest that targeted serum albumin screening in jaundiced neonates with these risk factors may improve identification of those at increased risk for bilirubin neurotoxicity, thereby aiding individualized management according to the 2022 American Academy of Pediatrics guidelines. The study highlights the need for further research to validate these associations and to explore the clinical implications of hypoalbuminemia in diverse neonatal populations.

Additional Information

  • Source:Journal of Neonatal - Perinatal Medicine. 2026/01, Vol. 19, Issue 1, p97
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2026
  • ISSN:1934-5798
  • DOI:10.1177/19345798251391017
  • Accession Number:189366382
  • Copyright Statement:Copyright of Journal of Neonatal - Perinatal Medicine is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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