JOURNAL ARTICLE

Investigators at King's College London Detail Findings in Schizophrenia (Associations Between Glutamate and Cerebral Blood Flow In Treatment-resistant Schizophrenia During Clozapine Treatment).

  • Published In: Mental Health Weekly Digest, 2026. P. 1796 1 of 2

  • Database: Psychology Source 2 of 2

Abstract

The article focuses on a study examining the relationship between glutamate levels and cerebral blood flow (CBF) in individuals with treatment-resistant schizophrenia (TRS) undergoing clozapine treatment. Conducted by researchers at King's College London, the study found that changes in striatal glutamate levels were positively associated with changes in striatal CBF after 12 weeks of treatment. Additionally, higher levels of glutamate and CBF prior to treatment correlated with greater improvements in symptom severity. The research suggests that further investigation into glutamate-CBF relationships in various stages of psychosis and with different antipsychotic medications could be beneficial. [Extracted from the article]

Additional Information

  • Source:Mental Health Weekly Digest. 2026/02, p1796
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2026
  • ISSN:1543-6616
  • Accession Number:191408394
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