JOURNAL ARTICLE

A Low-Dose Oxytocin Protocol Decreases Quantitative Blood Loss in Elective Cesarean Sections: A Single-Center, Retrospective Cohort Study.

  • Published In: Military Medicine, 2025, v. 190, n. 5/6. P. e1017 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Hood, Courtney R; Baxter, Brian J; Puccia, Alyssa R; Patzkowski, Michael S 3 of 3

Abstract

This article focuses on comparing quantitative blood loss (QBL) after elective cesarean deliveries using the Defense Health Agency’s (DHA) standardized low-dose oxytocin protocol versus a historically used high-dose strategy. The DHA’s protocol, issued in 2021 as part of the Postpartum Hemorrhage Bundle, involves a lower initial bolus and a regulated infusion of oxytocin, aiming to reduce postpartum hemorrhage (PPH). In a retrospective cohort study of low-risk patients, no statistically significant difference in blood loss or PPH incidence was found between the low-dose and high-dose groups after controlling for confounding factors. The study concludes that the DHA low-dose oxytocin protocol is as effective as high-dose regimens in managing uterine atony during elective cesarean deliveries, recommending further research on side effects, high-risk populations, and transfusion outcomes.

Additional Information

  • Source:Military Medicine. 2025/05, Vol. 190, Issue 5/6, pe1017
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:0026-4075
  • DOI:10.1093/milmed/usae545
  • Accession Number:184724901
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