JOURNAL ARTICLE

B - 22 Cerebral Blood Flow in Patients with Autism Spectrum Disorder.

  • Published In: Archives of Clinical Neuropsychology, 2023, v. 38, n. 7. P. 1386 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Stafford, Claire; Aronson, Rebecca; Golden, Charles; Willeumier, Kristen; Amen, Daniel 3 of 3

Abstract

The article focuses on investigating cerebral blood flow (CBF) differences in individuals with autism spectrum disorder (ASD), specifically examining hyperactivity in the parietal lobe. Using archival single-photon emission computed tomography (SPECT) data, the study compared CBF levels between 91 children with ASD and 2,983 controls, finding significantly lower CBF in multiple brain regions—including the cerebellum, frontal, occipital, temporal lobes, vermis, and subcortical areas—in the ASD group. These reduced CBF levels may be associated with difficulties in emotional regulation, sensory sensitivity, repetitive behaviors, and memory functioning observed in children with ASD. The findings provide insight into potential neurobiological underpinnings of behavioral and cognitive characteristics in ASD.

Additional Information

  • Source:Archives of Clinical Neuropsychology. 2023/10, Vol. 38, Issue 7, p1386
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2023
  • ISSN:0887-6177
  • DOI:10.1093/arclin/acad067.228
  • Accession Number:174275006
  • Copyright Statement:Copyright of Archives of Clinical Neuropsychology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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