JOURNAL ARTICLE

Seroepidemiology of Measles and Rubella Among Hong Kong Young Adults and the Humoral Responses of a Measles-Mumps-Rubella Booster Among Participants With Low Antibody Levels.

  • Published In: Journal of Infectious Diseases, 2024, v. 230, n. 6. P. 1367 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Chan, Jeffery C H; Leung, Daniel; Chan, Sau Man; Tam, Issan Y S; Lam, Jennifer H Y; Chan, Koon Wing; Zhang, Kaiyue; Chiu, Timothy L H; Yeung, Tom H M; Chung, Gabriel M H; Duque, Jaime S Rosa; Lau, Yu Lung 3 of 3

Abstract

This article focuses on the seroepidemiology of measles and rubella among young adults aged 18–30 years in Hong Kong and evaluates the humoral immune response to a measles, mumps, and rubella (MMR) vaccine booster in individuals with low antibody levels. The study found measles and rubella seroprevalence rates of 94.7% and 97.3%, respectively, with lower rates observed in the older subset (26–30 years), indicating an immunity gap. Among participants with vaccine failure (5.3% for measles and 2.7% for rubella), administration of an MMR booster induced significant increases in antibody levels one month postvaccination. The findings suggest that while Hong Kong maintains high vaccination coverage, waning immunity in certain age groups may warrant consideration of MMR booster doses to sustain measles and rubella elimination.

Additional Information

  • Source:Journal of Infectious Diseases. 2024/12, Vol. 230, Issue 6, p1367
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:0022-1899
  • DOI:10.1093/infdis/jiae297
  • Accession Number:181647843
  • Copyright Statement:Copyright of Journal of Infectious Diseases is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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