JOURNAL ARTICLE

Continuous preperitoneal versus thoracic epidural analgesia in open pancreatoduodenectomy: randomized clinical trial.

  • Published In: British Journal of Surgery, 2024, v. 111, n. 12. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Lee, Mirang; Jung, Ji-Yoon; Han, Youngmin; Chae, Yoon Soo; Yun, Won-Gun; Jung, Hye-Sol; Cho, Young Jae; Choi, Yoo Jin; Lee, Ho-Jin; Kwon, Wooil; Kim, Won Ho; Jang, Jin-Young 3 of 3

Abstract

This article reports on a randomized clinical trial comparing continuous preperitoneal wound infiltration (CWI) with thoracic epidural analgesia (TEA) for postoperative pain management after open pancreatoduodenectomy. The study found that CWI was non-inferior to TEA in controlling mean pain scores at rest during the first three postoperative days and provided superior pain relief and better quality of recovery on postoperative day 3. While TEA was associated with lower opioid consumption and earlier passage of flatus, it also had a higher incidence of postoperative hypotension. These results suggest that CWI may be a favorable alternative to TEA for pain management in open pancreatoduodenectomy, balancing effective analgesia with fewer complications.

Additional Information

  • Source:British Journal of Surgery. 2024/12, Vol. 111, Issue 12, p1
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:0007-1323
  • DOI:10.1093/bjs/znae296
  • Accession Number:183846512
  • Copyright Statement:Copyright of British Journal of Surgery is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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