Clinical Application of DynaCT in the Study of Vascular Neointimal Hyperplasia Characteristics after Option Filter Placement.

This study focuses on analyzing neointimal hyperplasia of the inferior vena cava (IVC) following implantation of the Option filter, a long-retrieval-window vena cava filter used to prevent pulmonary embolism. Using DynaCT imaging in 22 patients, the research identified that neointimal hyperplasia predominantly occurs around the filter's barbs, especially between the 1 to 5 clock points of the IVC, with thickness correlating significantly with the number of neointimal cuts required during filter retrieval. Although a linear trend was observed between hyperplasia thickness and filter implantation time, this correlation was not statistically significant, likely due to the filter's long implantation period exceeding four weeks. The findings suggest that modifying the filter retrieval catheter to control cutting force and direction can enable safe and effective removal of the filter despite neointimal hyperplasia, providing clinical guidance for managing long-term filter retrieval.