OVERVIEW OF IN VITRO METHODS FOR EVALUATING ANTICANCER ACTIVITY AND THE ANTICANCER POTENTIAL OF INDIAN MEDICINAL PLANTS.

This study aims to assess the anticancer potential of Indian medicinal plants using in vitro methods. Various plant extracts and bioactive compounds have shown promising anticancer activity against different cancer cell lines. Indian medicinal plants such as Curcuma longa (turmeric), Withania somnifera (ashwagandha), Azadirachta indica (neem), Ocimum sanctum (holy basil), Zingiber officinale (ginger), Momordica charantia (bitter melon), Moringa oleifera (moringa), and Aegle marmelos (bael) have demonstrated significant anticancer effects. These plants exhibit mechanisms like induction of apoptosis, inhibition of cell proliferation, suppression of inflammation, and prevention of metastasis. Active compounds, including curcumin, withanolides, and azadirachtin, have shown potential in targeting various cancer types, including breast, lung, and colon cancers. In vitro evaluations of Indian medicinal plants provide promising evidence of their anticancer potential. The bioactive compounds from these plants exhibit multiple mechanisms of action, such as apoptosis induction and cell cycle regulation. These findings underscore the need for further in vivo studies and clinical trials to validate the therapeutic potential of these plant-derived compounds for cancer treatment. [ABSTRACT FROM AUTHOR]