JOURNAL ARTICLE

Disrupted connectivity of the brainstem ascending reticular activating system nuclei-left parahippocampal gyrus could reveal mechanisms of delirium following basal ganglia intracerebral hemorrhage.

  • Published In: Mental Health Weekly Digest, 2025. P. 151 1 of 2

  • Database: Psychology Source 2 of 2

Abstract

The article focuses on a study investigating the functional connectivity (FC) of the ascending reticular activating system (ARAS) in patients experiencing delirium following intracerebral hemorrhage (ICH). The research identified significant disruptions in FC between the brainstem ARAS nuclei and the left parahippocampal gyrus in delirium patients, suggesting this disruption may contribute to the pathogenesis of delirium. The strength of this connectivity was found to be a reliable predictor of delirium onset, with a high predictive accuracy indicated by an area under the curve of 0.893. The findings highlight the potential for restoring normal connectivity as a strategy for early intervention in delirium. [Extracted from the article]

Additional Information

  • Source:Mental Health Weekly Digest. 2025/11, p151
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:1543-6616
  • Accession Number:189307971
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