JOURNAL ARTICLE

Reply: High‐dose oral glutamine can reduce cerebrospinal fluid glutamate in mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes without a beneficial clinical or cerebral tissue effect.

  • Published In: European Journal of Neurology, 2023, v. 30, n. 4. P. 1158 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Guerrero‐Molina, María Paz; Domínguez‐González, Cristina; González de la Aleja, Jesús 3 of 3

Abstract

High-dose oral glutamine supplementation reduces elevated glutamate levels in cerebrospinal fluid in patients with mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes syndrome. Reply: High-dose oral glutamine can reduce cerebrospinal fluid glutamate in mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes without a beneficial clinical or cerebral tissue effect We investigated the effect of high-dose oral glutamine supplementation on cerebrospinal fluid (CSF) glutamate levels in patients with mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes (MELAS) syndrome as a preliminary study to assess biochemical changes and the safety of the intervention. [Extracted from the article]

Additional Information

  • Source:European Journal of Neurology. 2023/04, Vol. 30, Issue 4, p1158
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2023
  • ISSN:1351-5101
  • DOI:10.1111/ene.15683
  • Accession Number:162243137
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