JOURNAL ARTICLE

Pregnancy and childbirth in Takayasu arteritis in Japan: A nationwide retrospective study.

  • Published In: Modern Rheumatology, 2025, v. 35, n. 2. P. 339 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Miyamae, Takako; Manabe, Yusuke; Sugihara, Takahiko; Umezawa, Natsuka; Yoshifuji, Hajime; Tamura, Naoto; Abe, Yoshiyuki; Furuta, Shunsuke; Nagafuchi, Hiroko; Ishizaki, Jun; Nakano, Naoko; Atsumi, Tatsuya; Karino, Kohei; Amano, Koichi; Kurasawa, Takahiko; Ito, Shuichi; Yoshimi, Ryusuke; Ogawa, Noriyoshi; Banno, Shogo; Naniwa, Taio 3 of 3

Abstract

This study focuses on the medical management and pregnancy outcomes of patients with Takayasu arteritis (TAK), a granulomatous large vessel vasculitis, in Japan. Analyzing 51 cases and 68 pregnancies from 2019 to 2021, the research found that most pregnancies were successfully managed with low-dose prednisolone (PSL ≤10 mg/day), with TAK relapse occurring in fewer than 20% of pregnancies during gestation and postpartum. While 20.9% of infants were preterm and 28.8% were low birth weight, no serious postnatal abnormalities were reported. The findings suggest that stable disease activity and appropriate treatment enable relatively safe pregnancies and deliveries in TAK patients.

Additional Information

  • Source:Modern Rheumatology. 2025/03, Vol. 35, Issue 2, p339
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:1439-7595
  • DOI:10.1093/mr/roae068
  • Accession Number:183846352
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