JOURNAL ARTICLE

Two cases of drug-induced psoriasis from second-generation androgen receptor blockers.

  • Published In: Clinical & Experimental Dermatology, 2025, v. 50, n. 5. P. 1035 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Buttars, Ben; Baltazar, Dave; Charest, Guy; Flaherty, Amber; Hamann, Dathan; Whittemore, Darren; Hamann, Carsten 3 of 3

Abstract

The article focuses on the potential link between second-generation androgen receptor antagonists (ARAs), specifically enzalutamide and apalutamide, and the development of drug-induced psoriasis in patients with advanced prostate cancer (PCa). It presents two case studies of elderly men who developed psoriatic lesions after starting treatment with these medications. Both patients had no prior history of psoriasis, and their conditions improved with topical treatment while continuing their ARA therapy. The article discusses the pathophysiology of drug-induced psoriasis and emphasizes the importance of weighing the benefits of continued ARA treatment against the side effects, particularly in older patients. [Extracted from the article]

Additional Information

  • Source:Clinical & Experimental Dermatology. 2025/05, Vol. 50, Issue 5, p1035
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:0307-6938
  • DOI:10.1093/ced/llae509
  • Accession Number:185321489
  • Copyright Statement:Copyright of Clinical & Experimental Dermatology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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