JOURNAL ARTICLE

Significance of miRNA-192 as a Prognostic Marker in Chronic Lymphocytic Leukemia.

  • Published In: QJM: An International Journal of Medicine, 2024, v. 117. P. ii83 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Ali Soliman, Samah Hussein; Shalaby, Nahela Ahmed; Gamal Eissa, Doaa Ahmed; El Dine Salem, Dalia Diaa 3 of 3

Abstract

The article presents multiple clinical studies focusing on biomarkers and genetic factors in various diseases. It highlights the diagnostic and prognostic value of serum eosinophil-derived neurotoxin (EDN) in pediatric bronchial asthma and preschool wheezes, showing elevated EDN levels correlate with eosinophilic inflammation. Another study evaluates microRNA-192 (miRNA-192) as a prognostic marker in chronic lymphocytic leukemia (CLL), finding its expression levels significantly associated with disease prognosis and clinical parameters. Additionally, the prevalence of BRCA1 and BRCA2 gene mutations was investigated in Egyptian breast cancer patients, with no mutations detected in the studied cohort. Lastly, the association of SMAD7 gene polymorphism with colorectal cancer risk was examined, suggesting a potential protective role of the C allele, though results were not statistically significant.

Additional Information

  • Source:QJM: An International Journal of Medicine. 2024/10, Vol. 117, pii83
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:1460-2725
  • DOI:10.1093/qjmed/hcae175.193
  • Accession Number:181635813
  • Copyright Statement:Copyright of QJM: An International Journal of Medicine is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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