JOURNAL ARTICLE

Researchers at National University Have Reported New Data on Autism Spectrum Disorders (Subtype-specific alterations in first- and higher-order thalamic reticular neurons in the Shank3 mutant mouse model of autism).

  • Published In: Mental Health Weekly Digest, 2025. P. 1141 1 of 2

  • Database: Psychology Source 2 of 2

Abstract

The article focuses on research regarding Autism Spectrum Disorders (ASD) and the thalamic reticular nucleus (TRN) in a mouse model. Conducted by researchers at the National University in Mexico City, the study investigates the differential changes in first-order (FO) and higher-order (HO) thalamic reticular neurons in Shank3 knockout mice, which are used as a model for ASD. Findings indicate that alterations in the inhibitory control of these neurons may contribute to sensory processing and sleep deficits commonly observed in individuals with ASD. The research highlights the importance of understanding the TRN's role in these developmental conditions. [Extracted from the article]

Additional Information

  • Source:Mental Health Weekly Digest. 2025/10, p1141
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:1543-6616
  • Accession Number:188416416
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