Altered states of consciousness in Danish healthy volunteers and recreational users of psilocybin and the possible impact of setting and intention: Danish validation of the five-dimensional altered states of consciousness questionnaire.

This article focuses on the validation of a Danish translation of the Five Dimensional Altered States of Consciousness Questionnaire (5D-ASC), a 94-item self-report instrument commonly used to measure acute psychedelic-induced altered states of consciousness (ASC). The study analyzed data from two samples: healthy volunteers administered psilocybin in a laboratory setting (N=47) and recreational psilocybin users reporting retrospectively via an online survey (N=550). Confirmatory factor analysis indicated that scoring the 5D-ASC using 11 subscales provided a better fit and good internal consistency compared to the original five-dimensional model. Additionally, 5D-ASC total scores correlated positively with psilocybin dose but showed no significant association with the setting or intention of use. The findings support the Danish 5D-ASC as a reliable and valid tool for assessing psychedelic-induced ASC, recommending further research to determine which scoring method best predicts clinical outcomes.