JOURNAL ARTICLE

A simple and low-cost paper-based device for simultaneous determination of hematocrit and hemoglobin levels in point-of-care settings.

  • Published In: Physics of Fluids, 2023, v. 35, n. 12. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Ram, Rishi; Kumar, Dharmendra; Paik, Pradip; Sarkar, Arnab 3 of 3

Abstract

The article focuses on the development and validation of a simple, inexpensive, and disposable microfluidic paper-based analytical device (μPAD) designed to simultaneously measure hematocrit and hemoglobin levels from small blood samples. The device determines hematocrit by analyzing the area of a blood stain on treated Whatman filter paper and estimates hemoglobin concentration through the gray color intensity of a lysed blood mixture stain, both quantified via scanned images. Validation against automated hematology analyzers showed high correlation (R² ≈ 0.97) and acceptable agreement, indicating the device's potential for point-of-care testing in resource-limited settings without requiring costly reagents or complex instrumentation.

Additional Information

  • Source:Physics of Fluids. 2023/12, Vol. 35, Issue 12, p1
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2023
  • ISSN:1070-6631
  • DOI:10.1063/5.0176299
  • Accession Number:174524392
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