The Effect of Algae Supplementation on Anthropometric Indices in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This article presents a systematic review and meta-analysis of 61 randomized controlled trials (RCTs) assessing the effects of algae supplementation—including Spirulina, Chlorella, and other types—on anthropometric indices in adults. The analysis found that algae supplementation was associated with statistically significant reductions in body mass index (BMI), body weight (BW), waist circumference (WC), body fat in kilograms, and body fat percentage, particularly in overweight or obese individuals and in studies lasting 10 weeks or longer. However, no significant effects were observed on hip circumference, waist-to-hip ratio, or lean body mass. The certainty of evidence ranged from very low to moderate due to heterogeneity among studies, variations in algae types, dosages, and study quality, leading the authors to recommend cautious interpretation of these findings.