(125) INTRAPARTUM AND 30-DAY POSTPARTUM COMPLICATIONS IN PREGNANCIES WITH ANTENATAL SARS-COV-2 INFECTION.

This study examines intrapartum and 30-day postpartum complications in pregnancies affected by antenatal SARS-CoV-2 (COVID-19) infection using a national electronic health record dataset from January 2020 to May 2023. Compared to matched controls without COVID-19, pregnant individuals with antenatal COVID-19 had increased risks of obstetric complications such as postpartum hemorrhage, gestational hypertension, pre-eclampsia, eclampsia, and preterm labor. They also faced higher risks of postpartum cardiovascular and neurovascular events, including cerebral infarction, pulmonary embolism, deep vein thrombosis, sepsis, heart failure, and cardiomyopathy. No significant increased risk was found for HELLP syndrome, placental abruption, or myocardial infarction. These findings suggest antenatal COVID-19 infection is a risk factor for various maternal complications during and shortly after delivery.