JOURNAL ARTICLE

The Pattern of Dissociative Symptoms Differs between Post-Traumatic Stress Disorder and First Esketamine Administration for Treatment-Resistant Depression.

  • Published In: Archives of Clinical Neuropsychology, 2024, v. 39, n. 7. P. 928 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Williamson, David; Bremner, J D; Vaccarino, Viola; Williamson, Linda 3 of 3

Abstract

This article examines differences in the pattern of dissociative symptoms between patients with Post-Traumatic Stress Disorder (PTSD) and those receiving their first administration of esketamine for Treatment-Resistant Depression (TRD). Data from 134 PTSD patients exposed to various traumas and 759 TRD patients undergoing initial esketamine treatment were analyzed. While dissociative symptoms were generally more prevalent in the esketamine group, PTSD patients more frequently reported dissociative amnesia and identity fragmentation, whereas esketamine-treated patients primarily experienced depersonalization and derealization. These findings suggest that the underlying causes of dissociative symptoms may differ between PTSD and esketamine treatment contexts.

Additional Information

  • Source:Archives of Clinical Neuropsychology. 2024/10, Vol. 39, Issue 7, p928
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:0887-6177
  • DOI:10.1093/arclin/acae067.010
  • Accession Number:184163301
  • Copyright Statement:Copyright of Archives of Clinical Neuropsychology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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