JOURNAL ARTICLE

A - 27 Early-Onset Alzheimer's Disease: Indications of Psychosis Severity and Disease Progression.

  • Published In: Archives of Clinical Neuropsychology, 2023, v. 38, n. 7. P. 1188 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Muscat, Whitney M; Arleo, Kayla 3 of 3

Abstract

This article focuses on a case study of Early-Onset Alzheimer’s Disease (EOAD), which accounts for about 5% of Alzheimer’s cases and is characterized by delayed diagnosis and aggressive progression. The study details a 63-year-old Hispanic woman exhibiting progressive cognitive decline alongside complex psychotic symptoms, including hallucinations and delusions linked to real-life events, contributing to social withdrawal and functional impairment. Neuroimaging revealed hypometabolism in parietotemporal and related brain regions, while cognitive testing showed deficits in processing speed, cognitive flexibility, and memory retention, with relatively preserved attention and working memory. The findings support EOAD diagnosis and highlight that behavioral changes, particularly psychosis, may indicate disease progression and severity.

Additional Information

  • Source:Archives of Clinical Neuropsychology. 2023/10, Vol. 38, Issue 7, p1188
  • Document Type:Case Study
  • Subject Area:Health and Medicine
  • Publication Date:2023
  • ISSN:0887-6177
  • DOI:10.1093/arclin/acad067.044
  • Accession Number:174274822
  • Copyright Statement:Copyright of Archives of Clinical Neuropsychology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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