JOURNAL ARTICLE

Histologic Glycogenic Acanthosis in the Distal Esophagus is Prevalent in Morbidly Obese Pediatric Patients Without Gastrointestinal Symptoms.

  • Published In: International Journal of Surgical Pathology, 2026, v. 34, n. 1. P. 106 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Krasinski, Claire A.; Wu, Hao 3 of 3

Abstract

The article focuses on glycogenic acanthosis (GA), a benign esophageal lesion that is often underreported due to its asymptomatic nature and lack of specific endoscopic findings. The study examines the prevalence of GA in pediatric patients undergoing prebariatric surgical evaluation, finding that 41% of these patients exhibited GA, compared to only 5% in a control group of symptom-driven esophageal biopsies. The research highlights potential associations between GA, obesity, and genetic conditions such as Cowden syndrome and tuberous sclerosis, which are linked to mutations in the PTEN gene and others. The findings suggest a need for further investigation into the relationship between GA and obesity in pediatric populations to avoid misdiagnosis and unnecessary treatments. [Extracted from the article]

Additional Information

  • Source:International Journal of Surgical Pathology. 2026/02, Vol. 34, Issue 1, p106
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2026
  • ISSN:1066-8969
  • DOI:10.1177/10668969251359942
  • Accession Number:190662336
  • Copyright Statement:Copyright of International Journal of Surgical Pathology is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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