Bone Marrow Aspirate Concentrate and Xenograft Versus Autograft and Xenograft in the 3D Reconstruction of Atrophic Maxillary Ridges: A Split-Mouth Randomized Controlled Trial.

This article reports on a split-mouth randomized controlled trial comparing bone marrow aspirate concentrate (BMAC) combined with xenograft versus autograft mixed with xenograft for three-dimensional (3D) reconstruction of vertically and horizontally atrophied maxillary ridges using prebent titanium (Ti) meshes. Ten fully edentulous patients underwent bilateral maxillary ridge augmentation, with one side treated using BMAC and xenograft (test side) and the other side using autograft and xenograft (control side). After six months, radiographic analysis showed comparable vertical and horizontal bone gains between groups, while histomorphometric analysis revealed significantly higher bone area percentage and mature bone formation in the BMAC group. The study concludes that 3D alveolar reconstruction with prebent Ti meshes loaded with xenograft mixed with BMAC is a reliable and less complicated alternative to autograft-based augmentation for severely atrophic maxillary ridges.