JOURNAL ARTICLE

Prediction of long-term outcomes in patients with chronic hepatitis D infection by quantitative HBcrAg/anti-HBc IgG ratio.

  • Published In: Minerva Biotechnology & Biomolecular Research, 2024, v. 36, n. 4. P. 174 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Dileo, Eleonora; Olivero, Antonella; Risso, Alessandra; Troshina, Giulia; Ciancio, Alessia; CAVIGLIA, Gian Paolo 3 of 3

Abstract

This article focuses on the predictive value of hepatitis B virus (HBV) biomarkers for long-term clinical outcomes in patients with chronic hepatitis D (CHD) infection. In a retrospective study of 82 CHD patients, the hepatitis B core-related antigen (HBcrAg) and the ratio of HBcrAg to quantitative antibodies to hepatitis B core antigen (anti-HBc IgG) were measured at baseline and found to be significantly associated with increased risks of hepatocellular carcinoma, liver-related events, and mortality over a median follow-up of 8 years. The study suggests that combined measurement of HBcrAg and anti-HBc IgG may serve as a useful tool for risk stratification and personalized management in CHD patients. Limitations include the retrospective design and relatively small sample size, indicating the need for further validation in larger cohorts.

Additional Information

  • Source:Minerva Biotechnology & Biomolecular Research. 2024/12, Vol. 36, Issue 4, p174
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:2724-542X
  • DOI:10.23736/s2724-542X.24.03177-8
  • Accession Number:181431655
  • Copyright Statement:Copyright of Minerva Biotechnology & Biomolecular Research is the property of Edizioni Minerva Medica and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Looking to go deeper into this topic? Look for more articles on EBSCOhost.