JOURNAL ARTICLE

Maintaining breed integrity: Successful introgression of the SLICK1 allele into the Holstein breed.

  • Published In: Journal of Heredity, 2025, v. 116, n. 3. P. 216 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Zayas, Gabriel A; Dikmen, Serdal; Mateescu, Raluca G; Hansen, Peter J 3 of 3

Abstract

This article focuses on the genetic introgression of the SLICK1 allele from Senepol cattle into Holstein cattle to improve thermotolerance. The SLICK1 allele, located in the prolactin receptor gene (PRLR) on Bovine Autosome 20 (BTA20), produces a dominant short and sleek hair coat that enhances heat stress adaptation. Using genotyping and breed of origin analyses, the study confirmed successful introgression of the SLICK1 allele into University of Florida Holsteins with minimal Senepol genetic material retained outside the PRLR locus, except for a secondary region on BTA4 linked to heat stress adaptation. These findings demonstrate that targeted introgression can improve livestock resilience to thermal stress while maintaining breed integrity, offering a model for breeding programs addressing climate change challenges.

Additional Information

  • Source:Journal of Heredity. 2025/05, Vol. 116, Issue 3, p216
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:0022-1503
  • DOI:10.1093/jhered/esae057
  • Accession Number:186054073
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