JOURNAL ARTICLE

Elevated skin perfusion pressure 48 hours after endovascular therapy predicts early wound healing in chronic limb-threatening ischemia.

  • Published In: Vascular Medicine, 2026, v. 31, n. 2. P. 165 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Jeon, Bo Kyung; Ko, Young-Guk; Lee, Seung-Jun; Ahn, Chul-Min; Lee, Sang-Hyup; Lee, Yong-Joon; Hong, Sung-Jin; Kim, Jung-Sun; Kim, Byeong-Keuk; Choi, Donghoon; Hong, Myeong-Ki 3 of 3

Abstract

This study focuses on comparing skin perfusion pressure (SPP) and transcutaneous oxygen pressure (TcPO₂) for predicting early wound healing after endovascular therapy (EVT) in patients with chronic limb-threatening ischemia (CLTI). Analyzing 99 limbs from 87 patients, the study found that a high post-EVT SPP (≥48 mmHg) within 48 hours significantly predicted early wound healing and was associated with lower rates of repeat revascularization at 6 months. In contrast, post-EVT TcPO₂ (≥27 mmHg) did not predict early wound healing but correlated with reduced repeat revascularization and major adverse limb events (MALE). Neither SPP nor TcPO₂ was linked to mortality or major amputation, suggesting that SPP may provide more reliable early prognostic information, while TcPO₂ may reflect other clinical outcomes in CLTI management.

Additional Information

  • Source:Vascular Medicine. 2026/04, Vol. 31, Issue 2, p165
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2026
  • ISSN:1358-863X
  • DOI:10.1177/1358863X251414636
  • Accession Number:193250239
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