JOURNAL ARTICLE

(299) The Modulating Effects of Follicle Stimulating Hormone and Clomid on Men with Azoospermia or Oligozoospermia Taking Human Chorionic Gonadotropin.

  • Published In: Journal of Sexual Medicine, 2024. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Kassab, J; Garcia Keeme-Sayre, A; Lindsey Ii, J; Torres-Anguiano, J; Lipshultz, L 3 of 3

Abstract

This article focuses on comparing the effects of combining human chorionic gonadotropin (hCG) with either follicle stimulating hormone (FSH) or Clomid on men with azoospermia or oligozoospermia. The study found that men treated with hCG plus FSH showed greater improvements in serum testosterone levels and total sperm counts over multiple follow-up visits compared to those receiving hCG plus Clomid. The authors suggest that hCG combined with FSH directly stimulates spermatogenesis more effectively than hCG with Clomid, which acts indirectly via pituitary stimulation. The availability of compounded FSH at reduced cost may facilitate wider use of this treatment approach for hypogonadal patients seeking improved fertility outcomes.

Additional Information

  • Source:Journal of Sexual Medicine. 2024/01, p1
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:1743-6095
  • DOI:10.1093/jsxmed/qdae001.285
  • Accession Number:175496012
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