JOURNAL ARTICLE

Breast Surgical Conservation Therapy versus Mastectomy in Multifocal or Multicentric Breast Cancer; A Systematic Review and Meta-Analysis.

  • Published In: QJM: An International Journal of Medicine, 2024, v. 117. P. ii135 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: El-Moghny, Ashraf Abd; Nabil, Ahmed; Hanafy, Dina Mohamed; Korany Mahmoud, Reem Mohamed 3 of 3

Abstract

The article systematically reviews and meta-analyzes the outcomes of breast surgical conservation therapy (BCT) versus mastectomy in patients with multifocal (MF) or multicentric (MC) breast cancer, defined as multiple synchronous ipsilateral tumors separated by varying distances within the breast. Analyzing twelve trials involving 1,906 patients, the study found no statistically significant differences in local or regional recurrence, distant metastasis, or overall survival between BCT and mastectomy groups. The findings suggest that BCT is a feasible surgical option for MF/MC breast cancer patients, though the authors recommend further prospective studies to optimize treatment and prognosis.

Additional Information

  • Source:QJM: An International Journal of Medicine. 2024/10, Vol. 117, pii135
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:1460-2725
  • DOI:10.1093/qjmed/hcae175.313
  • Accession Number:181635932
  • Copyright Statement:Copyright of QJM: An International Journal of Medicine is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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