JOURNAL ARTICLE

Palladium‐Catalyzed Enantioselective [4+2] Cycloaddition of 4‐Vinylbenzodioxinones with Barbiturate‐Derived Alkenes: Con‐struction of Chiral Spirobarbiturate−Chromanes.

  • Published In: Chemistry - A European Journal, 2024, v. 30, n. 24. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Tang, Yi; Huang, Mingxia; Ding, Siyuan; Liu, Xinyao; Huyang, Xiaochun; Wang, Bo; Guo, Hongchao 3 of 3

Abstract

In this paper, Pd‐catalyzed [4+2] decarboxylative cycloaddition of 4‐vinylbenzodioxinones with barbiturate‐derived alkenes has been developed, leading to various spirobarbiturate−chromane derivatives in high yields with excellent diastereo‐ and enantioselectivities. The scale‐up reaction and further derivation of the product were demonstrated. A plausible reaction mechanism was also proposed. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Chemistry - A European Journal. 2024/04, Vol. 30, Issue 24, p1
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:0947-6539
  • DOI:10.1002/chem.202400302
  • Accession Number:177040869
  • Copyright Statement:Copyright of Chemistry - A European Journal is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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