JOURNAL ARTICLE

Researchers from Icahn School of Medicine at Mount Sinai Describe Findings in Schizotypal Personality Disorders (Investigation of Brain White Matter and Social Cognition In Schizophrenia and Schizotypal Personality Disorder Using Neurite...).

Published In: Mental Health Weekly Digest, 2025. P. 463 1 of 2
Database: Psychology Source 2 of 2

Abstract

The article focuses on a study investigating brain white matter abnormalities in Schizotypal Personality Disorder (SPD) and schizophrenia, utilizing neurite orientation dispersion density imaging (NODDI). Conducted by researchers at the Icahn School of Medicine at Mount Sinai, the study found that individuals with schizophrenia exhibited lower fractional anisotropy (FA) in specific brain regions compared to healthy controls, while the SPD group showed intermediate FA levels. The research suggests that alterations in extracellular fiber coherence may serve as an intermediate phenotype for future studies in the schizophrenia spectrum. The study was funded by various U.S. health organizations, including the National Institute of Mental Health (NIMH). [Extracted from the article]

Additional Information

Source:Mental Health Weekly Digest. 2025/07, p463
Document Type:Article
Subject Area:Health and Medicine
Publication Date:2025
ISSN:1543-6616
Accession Number:186220662
Copyright Statement:Copyright of Mental Health Weekly Digest is the property of NewsRx and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Looking to go deeper into this topic? Look for more articles on EBSCOhost.