JOURNAL ARTICLE

Plexiform Fibromyxoma of the Gastric Body: A Rare Benign Mesenchymal Tumor in an Unconventional Location.

  • Published In: International Journal of Surgical Pathology, 2026, v. 34, n. 2. P. 513 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Bseiso, Anan; Ibrahim, Dalia 3 of 3

Abstract

This article focuses on plexiform fibromyxoma (PF), an exceptionally rare benign mesenchymal tumor primarily affecting the gastric antrum and body. It presents a detailed case of a 67-year-old female patient diagnosed with PF in the proximal gastric body following endoscopic mucosal resection of a submucosal lesion initially suspected to be a gastrointestinal stromal tumor (GIST). The report emphasizes the distinct histological and immunohistochemical features of PF, including positivity for smooth muscle actin and negativity for KIT and DOG1, which differentiate it from other gastrointestinal mesenchymal tumors. Management typically involves surgical or endoscopic resection, with generally favorable prognosis, though recent evidence suggests potential for aggressive behavior, underscoring the need for careful diagnosis and follow-up.

Additional Information

  • Source:International Journal of Surgical Pathology. 2026/04, Vol. 34, Issue 2, p513
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2026
  • ISSN:1066-8969
  • DOI:10.1177/10668969251379899
  • Accession Number:191423578
  • Copyright Statement:Copyright of International Journal of Surgical Pathology is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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