JOURNAL ARTICLE

Audacity of gene therapy.

  • Published In: British Journal of Dermatology, 2024, v. 191, n. 6. P. 1009 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Dimitrov, Marketa; Ebens, Christen L; Tolar, Jakub 3 of 3

Abstract

The article discusses the evolution of gene therapy, focusing on the treatment of various genetic disorders through different gene-targeting strategies. It highlights successful gene therapy approaches for haemoglobinopathies, inherited metabolic disorders, and genodermatoses. The text also addresses the challenges and risks associated with gene therapy, such as insertional oncogenesis and immunogenicity. Access to gene therapy is primarily through clinical trials, with efforts to broaden access to resource-constrained countries ongoing. The article emphasizes the need for continued refinement of gene therapy manufacturing to optimize treatment accessibility and effectiveness. [Extracted from the article]

Additional Information

  • Source:British Journal of Dermatology. 2024/12, Vol. 191, Issue 6, p1009
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:0007-0963
  • DOI:10.1093/bjd/ljae332
  • Accession Number:180921794
  • Copyright Statement:Copyright of British Journal of Dermatology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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