JOURNAL ARTICLE

The impact of restricted chests on long-term lung function parameters following lung transplantation in patients with interstitial lung disease.

  • Published In: European Journal of Cardio-Thoracic Surgery, 2025, v. 67, n. 1. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Nakanishi, Keita; Schweiger, Thomas; Schwarz, Stefan; Taghavi, Shahrokh; Hillebrand, Caroline; Begic, Merjem; Auner, Sophia; Boehm, Panja M; Mosleh, Berta; Jaksch, Peter; Benazzo, Alberto; Chen-Yoshikawa, Toyofumi Fengshi; Hoetzenecker, Konrad 3 of 3

Abstract

This study investigates how disparities between actual and predicted total lung capacity (TLC) in patients with interstitial lung disease (ILD) affect perioperative outcomes, lung function, and long-term survival following lung transplantation (LTx). In a retrospective analysis of 170 ILD patients undergoing double LTx at a European center, patients were divided into groups with low (<0.55) and high (≥0.55) ratios of actual to predicted TLC. Results showed no significant differences between groups in perioperative complications, long-term lung function, or five-year overall survival, despite early postoperative lung function being better in the high ratio group. These findings suggest that chest wall compliance improves and remodels over time after LTx, even in patients with severely restricted chest cavities.

Additional Information

  • Source:European Journal of Cardio-Thoracic Surgery. 2025/01, Vol. 67, Issue 1, p1
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:1010-7940
  • DOI:10.1093/ejcts/ezae465
  • Accession Number:182905374
  • Copyright Statement:Copyright of European Journal of Cardio-Thoracic Surgery is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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