JOURNAL ARTICLE

Metabolic adaptations in McArdle's disease and its mechanisms.

  • Published In: Journal of Physiology, 2023, v. 601, n. 6. P. 1051 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Santos, Pedro Henrique Silva; Rodrigues, Luis Felipe; Improta‐Caria, Alex Cleber; Voltarelli, Vanessa Azevedo 3 of 3

Abstract

Muscle glycogen unavailability and fat oxidation rate during exercise: Insights from McArdle disease. Keywords: glycogen and exercise; metabolism EN glycogen and exercise metabolism 1051 1052 2 03/17/23 20230315 NES 230315 The first records in the 1950s (McArdle, [2]) show that McArdle's disease affects one in every 100 000 individuals. Moreover, the increased MFO rate in McArdle's patients was reached in a significant higher workload compared to healthy controls, suggesting that these patients are better adapted to use fat as a substrate to sustain exercise. [Extracted from the article]

Additional Information

  • Source:Journal of Physiology. 2023/03, Vol. 601, Issue 6, p1051
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2023
  • ISSN:0022-3751
  • DOI:10.1113/JP284118
  • Accession Number:162434633
  • Copyright Statement:Copyright of Journal of Physiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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