JOURNAL ARTICLE

Tic‐tac‐mito: The relationship between the biological clock with mitochondria dynamics and skeletal muscle function in humans.

  • Published In: Journal of Physiology, 2024, v. 602, n. 23. P. 6439 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Jesus, Itamar C. G.; Araujo, Flavia M. 3 of 3

Abstract

The article explores the relationship between the biological clock, mitochondria dynamics, and skeletal muscle function in humans. It discusses the role of clock proteins BMAL1 and CLOCK in regulating metabolic processes and muscle health. The study by Figueroa-Toledo et al. focuses on the association between BMAL1 and CLOCK protein mass with mitochondrial dynamics and skeletal muscle quality markers in non-athletic, non-obese, and non-diabetic males. The findings suggest a link between clock proteins and mitochondria organization within muscle fibers, as well as their impact on protein synthesis pathways and muscle strength. Further research is needed to understand the specific roles of clock proteins in skeletal muscle health and disease models. [Extracted from the article]

Additional Information

  • Source:Journal of Physiology. 2024/12, Vol. 602, Issue 23, p6439
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:0022-3751
  • DOI:10.1113/JP287210
  • Accession Number:181226363
  • Copyright Statement:Copyright of Journal of Physiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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