Effect of Autogenic Relaxation Training on Irritable Bowel Syndrome In Adult Females.

This article reports on a newly registered clinical trial (NCT07533500) conducted by Cairo University to evaluate the effect of autogenic relaxation training (ART) on irritable bowel syndrome (IBS) in adult females aged 20 to 35 years with constipation-predominant IBS. The randomized, single-masked interventional study compares ART combined with aerobic exercise and lifestyle modification against aerobic exercise and lifestyle modification alone over eight weeks. Primary outcomes include IBS symptom severity, bowel movement frequency, fatigue impact, anxiety and depression levels, quality of life, and cortisol levels. The trial aims to assess whether ART, a relaxation technique involving mental exercises to reduce sympathetic nervous system activity, can improve IBS symptoms and associated psychological factors. Recruitment is planned in Egypt with an enrollment target of 44 participants and primary completion expected by August 2026. [Extracted from the article]